Laser Technician IBEC Board Exam 2026 – 400 Free Practice Questions to Pass the Exam

Acanthosis nigricans is a skin condition characterized by dark, velvety patches that typically appear in body folds and creases, such as the neck, armpits, and groin. It is most commonly associated with conditions that involve insulin resistance, such as diabetes and obesity. In these instances, the excess insulin signals keratinocytes and fibroblasts to increase their proliferation, leading to the thickened, darkened skin often seen in acanthosis nigricans.

This association is particularly evident in individuals with type 2 diabetes, where elevated insulin levels contribute to the development of this condition. Obesity is another significant risk factor, as increased adipose tissue can lead to higher insulin resistance, further exacerbating the likelihood of developing acanthosis nigricans.

The other options listed, while they refer to various skin disorders and conditions, do not have the same strong connection with acanthosis nigricans as diabetes and obesity do. Hyperthyroidism, psoriasis, eczema, and allergic reactions do not directly link with the underlying mechanism that leads to the thickening and darkening of skin seen in acanthosis nigricans.